1.
Indian Pediatr
;
2016 Apr; 53(4): 349-350
Article
in English
| IMSEAR
| ID: sea-178979
ABSTRACT
Background: Severe pulmonary hypertension may following ibuprofen administration for ductal closure. Case characteristics: An extremely preterm infant who developed severe pulmonary hypertension unresponsive to inhaled nitric oxide after ibuprofen administration. Outcome: Pulmonary hypertension reversed after the administration of oral sildenafil, but the infant died due to complications related to bronchopulmonary dysplasia. Message: Sildenafil may have a role in treatment of severe pulmonary hypertension after ibuprofen treatment for ductal closure.